LOCATIONS: NEW YORK CITY | LONG ISLAND
Curious about starting treatment? Give us a call at (917)-261-7370 or book a free consultation to learn more!
Complex Regional Pain Syndrome (CRPS) is one of the most challenging pain conditions to diagnose and treat. Characterized by intense, burning pain—often accompanied by changes in skin color, temperature, or swelling—CRPS typically begins after an injury or surgery but persists long after the tissue has healed. This condition doesn’t just affect the body; it can profoundly impact a person’s ability to function, work, or engage in daily activities.
What makes CRPS so debilitating is its underlying mechanism: a malfunction in the central and peripheral nervous systems. As a result, the body continues to send exaggerated pain signals from the affected area to the brain, even in the absence of ongoing damage. Traditional treatments—such as opioids, nerve blocks, physical therapy, or corticosteroids—may provide limited short-term relief but often fall short in delivering sustained, long-term improvement.
At NY Ketamine Infusions, we specialize in treating CRPS using intravenous ketamine infusions—an evidence-supported therapy that works directly on the neurological pathways responsible for chronic, neuropathic pain. Our approach is designed to offer more than symptom management. We aim to reduce central sensitization, calm hyperactive pain signaling, and help patients reclaim mobility, comfort, and control.
CRPS is driven by a combination of peripheral nerve dysfunction and central nervous system sensitization. In simple terms, the nervous system becomes “rewired” to misinterpret normal sensory input as pain—causing ordinary touch, movement, or temperature changes to feel excruciating. Over time, this hypersensitive state can spread beyond the original site of injury, affecting nearby tissues and further complicating treatment.
Ketamine is uniquely positioned to address this complexity. As an NMDA receptor antagonist, ketamine blocks the overactivation of glutamate—one of the main neurotransmitters involved in amplifying pain signals. By dampening this excessive activity, ketamine helps “reset” the pain-processing systems of the brain and spinal cord. This allows patients to experience pain reduction not just during the infusion, but long afterward.
What sets ketamine apart from other CRPS interventions is its ability to interrupt pain memory and disrupt the feedback loops that reinforce chronic discomfort. Instead of masking symptoms, it facilitates real neurochemical change. Patients at NY Ketamine Infusions frequently describe improvements in burning or stabbing sensations, reduced hypersensitivity to touch or
temperature, and an enhanced ability to move or bear weight on the affected limb—all within days or weeks of beginning treatment.
If CRPS has taken control of your body and disrupted your life, ketamine therapy may offer the breakthrough you’ve been waiting for. Schedule your free consultation with NY Ketamine Infusions and discover how our team can help reduce your pain, improve your mobility, and restore your independence. We proudly serve patients from New York City, Long Island, and Westchester.
Conditions Treated
75 Maiden Lane, 10th Floor, New York, NY 10038
Phone: 917-261-7370
Treatment Hours:
7 days a week: 9AM to 7PM
150 Broadhollow Rd, Suite 103, Melville, NY 11747
Phone: 631-629-4626
Treatment Hours:
Monday, Wednesday, Friday from 9AM to 5PM
Our protocol requires a brief intake conversation with one of our physicians to determine if ketamine is likely to help you. Please fill out the form below and you will be contacted by our Patient Care Team within 24 hours. After submitting, you’ll get the opportunity to provide more personal information via an optional questionnaire.
